First 500 km

First 500 are super important. No kidding.
It not just engine run but also tyres and brake system.

New tyres have to be "run in" since they do not offer optimal grip at first. You should take account of this fact for the first 500 kilometres and drive particularly carefully

Allow for the fact that new brake pads do not achieve their full braking efficiency until approximately 200 kilometres. New brake pads must be first "run in" before they develop their optimal friction force.

And I decided to do that in one-two days. Best time is Friday late evening and Saturday day when roads are almost empty and no road works. Keep revolutions counter below 2500 and set speed limit to 100 km/h.

I took route from Netanya to end of Ayalon (road 20) to Moshe Dayan interchange now directly to Haifa and back ;-) You can stop by Ben Gurion airport on road 412 (near Tsafriya) to see how planes arrives and goes to sky.

Don't try road 4 - vary bad and wavy after Tel Aviv to Ashdod.
Also, road 2 after Netanya to the North about 3 kilometers is very crapy, stay on left line if possible.

Image source: http://he.wikipedia.org/wiki/נתיבי איילון